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Person in dark shirt sits at computer in cozy room with fireplace, bookshelf and wall clock, taking a moment to disengage from online cognitive training and look out the window,

Cognitive Training Improves Executive Function and Self-Efficacy in Young Women With Chronic Stroke: A Pilot Study

Frontiers in Human Neuroscience

Michelle S. Scheffler, Asha K. Vas, Catherine Cooper Hay, Lisa Griggs-Stapleton and Lori G. Cook

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OVERVIEW

Stroke is no longer just an older adult's condition — young women are increasingly experiencing strokes, often facing persistent difficulty with executive function, the cluster of mental skills that powers planning, problem-solving and memory. These deficits strike at a particularly demanding life stage, when women are managing careers, education, childcare and relationships — all of which depend heavily on sharp cognitive performance. Yet this population has been largely overlooked in rehabilitation research. This pilot study tests whether a SMART™ (Strategic Memory Advanced Reasoning Training), a structured, strategy-based cognitive training program, can meaningfully improve executive function and daily-life confidence in young women living with the long-term effects of stroke.Researchers enrolled eight women with chronic-stage stroke (average age ~39) and eight age- and education-matched women without stroke as a comparison group. All participants completed 10 one-hour SMART sessions over five weeks, delivered virtually via Zoom, making the program accessible regardless of where participants lived. The SMART program trained three core thinking strategies: filtering out noise to focus on what matters most, drawing big-picture meaning from complex information, and staying mentally flexible. Before and after training, participants were assessed on measures of executive function, daily living skills, self-confidence in cognitive tasks, community integration, and emotional well-being including depression, anxiety and stress.The results paint an encouraging picture. Women with stroke showed statistically significant improvements in abstraction, strategic memory, fluency of ideas, cognitive self-efficacy and stress — all with large effect sizes, a strong signal even in a small sample. Participants also rated the program highly for acceptability and real-world fit, and many reported applying SMART strategies directly to workplace and home challenges. The findings point to two priority areas for future research: larger, fully-powered clinical trials to confirm these results at scale, and routine executive function screening for young stroke survivors, whose cognitive difficulties are often overlooked because stroke at a young age is frequently — and incorrectly — assumed to mean better outcomes. The success of the virtual delivery format also opens the door to reaching young women who lack access to traditional in-person rehabilitation.
Figure 1. (A) Picture themes and (B) proverb interpretation scores in stroke and control groups.

Figure 1. (A) Picture themes and (B) proverb interpretation scores in stroke and control groups.

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Lori Cook in a blue blouse with blue lights, portrait. Director of Clinical Research, BrainHealth Research; Head of Research, The BrainHealth Project; Adjunct Assistant Professor, School of Behavioral and Brain Sciences

Lori Cook, PhD, CCC-SLP

Director of Clinical Research Head of Research, The BrainHealth Project Adjunct Assistant Professor, School of Behavioral and Brain Sciences


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