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Novel Oppositional Defiant Disorder 6 Months After Traumatic Brain Injury in Children and Adolescents

Energetic preteen/teenage male footballers cheering and punching the air as they run onto the field for a practice session.

The Journal of Neuropsychiatry and Clinical Neurosciences

Daniel S. Lowet, Anish Kolan, Florin Vaida, John R. Hesselink, Harvey S. Levin, Linda Ewing-Cobbs, Russell J. Schachar, Sandra B. Chapman, Erin D. Bigler, Elisabeth A. Wilde, Ann E. Saunders, Tony T. Yang, Olga Tymofiyeva, Hattan Arif and Jeffrey E. Max

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This study investigates possible predictive factors of novel oppositional defiant disorder (ODD) among children and adolescents over six months following traumatic brain injury (TBI). 177 children and adolescents (ages 5-14) with history of TBI were recruited to participate in biosocial testing. Assessments were conducted soon after injury (baseline) and considered preinjury characteristics (e.g., psychiatric disorders, adaptive function, family function, psychosocial adversity, family psychiatric history, socioeconomic status, injury severity, and postinjury processing speed). MRI analyses were conducted to examine potential brain lesions. Psychiatric outcome was assessed 6 months after the injury, and participants without preinjury ODD or similar challenges returned for a follow-up assessment.  Findings show an important minority of participants with TBI developed ODD, suggesting variables like socioeconomic status, lower family function, psychosocial adversity, and processing speed, may significantly increase risk.

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Sandra Bond Chapman, PhD

Chief Director Dee Wyly Distinguished Professor, School of Behavioral and Brain Sciences Co-Leader, The BrainHealth Project

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