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There are many unanswered questions when it comes to quantifying how the brain computes ‘self’,” said Dr. Gu. “Better understanding this could lead to breakthroughs in psychiatric disorders that involve aberrant self-processing such as anorexia nervosa, schizophrenia, autism spectrum disorder, major depression, and borderline personality disorder.
Citing studies that used quantitative measures of the self vs. others, a simple example looked at the differences in processing speed.
When shown information related to strangers, friends and themselves, participants were able to process information and make decisions much more quickly when it related to themselves instead of others.
Drs. Gu and Sui also cited studies in which areas of the brain associated with decision-making acted very differently in a mock investment situation depending on who and how much was at risk.
Depending on whether the person was making his or her own investment or watching someone making their investments, researchers observed differences in the anterior cingulate cortex.
Activity in another region of the brain, the insula cortex, correlated with the amount of the investment. For people with borderline personality disorder, insula activity was at compared to typical individuals when observing the other, but normal in the self-case. The opposite was true for people on the autism spectrum in the study. They showed normal activity in the other case and diminished activity in the self-case.
Drs. Gu and Sui concluded, “Thus, the paradigms and models reviewed here could potentially provide valuable insights into the mechanisms of mental illness.”CONTACT
Stephanie Hoefken
972.883.3221
stephanie.hoefken@utdallas.eduABOUT CENTER FOR BRAINHEALTH
Center for BrainHealth®, part of The University of Texas at Dallas, is a translational research institute committed to enhancing, preserving, and restoring brain health across the lifespan. Major research areas include the use of functional and structural neuroimaging techniques to better understand the neurobiology supporting cognition and emotion in health and disease. This leading-edge scientific exploration is translated quickly into practical innovations to improve how people think, work and live, empowering people of all ages to unlock their brain potential. Translational innovations build on Strategic Memory Advanced Reasoning Tactics (SMART™), a proprietary methodology developed and tested by BrainHealth researchers and other teams over three decades.
