Psychosis Risk and Resilience During Adolescence: Insights from Women’s Neurodevelopment

Despite growing focus on the early identification, intervention and prevention of psychosis in adolescence, little attention has been given to understanding the neurodevelopmental and pubertal context that the precede psychosis onset. This period is also marked by initiation and rising gonadal hormones, which have a powerful impact on the neuromaturation, connectivity and cognitive function. This developmental context may help explain sex differences in timing of psychosis onset and course. Hormones like estrogen effect normative neurodevelopment and may provide resiliency to women who are otherwise at risk for psychosis.

Dr. Damme's research leverages normative changes in late childhood and early adolescent development provides a natural experiment to understanding the neurodevelopmental interactions estrogen has with vulnerability to psychosis. Register for Virtual Register for virtual to receive updates on talks and online access to our full virtual season.

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