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Center for BrainHealth Investigates the Relationship Between Cannabis Use, Sleep and Memory

Francesca Filbey, PhD, and her lab outside Center for BrainHealth.

Center for BrainHealth

Sleep difficulties were associated with poorer memory performance.The growing legal use of recreational and medical cannabis has generated an increased concern for potential side effects from long-term use, particularly regarding problems with memory and sleep. Until now, the effect of cannabis use on sleep and on memory have only been studied separately. Research led by Francesca Filbey, PhD, from the Laboratory of Neuroimaging of Reward Dynamics at The University of Texas at Dallas’ Center for BrainHealth, in collaboration with a team from the University of Amsterdam, aimed to fill this gap by testing how sleep impacts memory among cannabis users. The study, “The Role of Sleep in the Link Between Cannabis Use and Memory Function: Evidence From a Cross-Sectional Study” was recently published in The American Journal of Drug and Alcohol Abuse.A total of 141 adults with cannabis use disorder (CUD, defined as using cannabis regularly, more than 5 days per week during the past year) and 87 non-current users participated in this study. Participants self-reported their frequency of sleep problems within the past week and completed a variety of cognitive assessments that tested their verbal memory, visuospatial learning and memory performance.Results revealed that the CUD group reported more sleep problems than the non-CUD group, and that this contributed to visuospatial memory problems as well. There was no difference between the two groups in verbal memory performance. Lead author Tracy Brown, a UT Dallas psychology PhD student in Dr. Filbey’s lab, stated, “Although sleep is one of the primary reasons people use cannabis, our findings suggest that long-term cannabis use actually results in poorer sleep, which is associated with poorer memory. These findings are useful to inform the consumers, clinicians and policymakers about the therapeutic considerations for cannabis, particularly regarding its use as a sleep aid.”He added, “For researchers, this study points to the importance of analyzing sleep when evaluating the effects of cannabis on brain health.”This research was supported by grant 1R01 DA042490 from the National Institute on Drug Abuse/National Institute of Health.ABOUT CENTER FOR BRAINHEALTHCenter for BrainHealth®, part of The University of Texas at Dallas, is a translational research institute committed to enhancing, preserving, and restoring brain health across the lifespan. Major research areas include the use of functional and structural neuroimaging techniques to better understand the neurobiology supporting cognition and emotion in health and disease. This leading-edge scientific exploration is translated quickly into practical innovations to improve how people think, work and live, empowering people of all ages to unlock their brain potential. Translational innovations build on Strategic Memory Advanced Reasoning Tactics (SMART™), a proprietary methodology developed and tested by BrainHealth researchers and other teams over three decades.Media Contact Shawn Williams, Allyn Media 214.923.5013 shawn@allynmedia.com

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Francesca Filbey, PhD

Bert Moore Endowed Chair and Professor, School of Behavioral and Brain Sciences Director, Cognitive Neuroscience Laboratory of Addictive Disorders

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2016 Friends of BrainHealth Award Recipients

The Friends of BrainHealth, a circle of donors supporting the Center for BrainHealth at UT Dallas, awarded four $25,000 Distinguished New Scientists Awards at the annual Friends of BrainHealth Scientist Selection Luncheon recently at the Dallas Country Club. The four scientists will use the funding to lead independently designed research studies.