Facebook pixelRelationship of Parieto-Occipital Brain Energy Phosphate Metabolism and Cognition Using 31P MRS at 7-Tesla in Amnestic Mild Cognitive Impairment
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Relationship of Parieto-Occipital Brain Energy Phosphate Metabolism and Cognition Using 31P MRS at 7-Tesla in Amnestic Mild Cognitive Impairment

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Frontiers in Aging Neuroscience

Namrata Das, Jimin Ren, Jeffrey S. Spence, Audette Rackley and Sandra Bond Chapman

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Overview

In this study, researchers identify mild cognitive impairment (MCI) as a potential area to determine the relationship between cognitive and brain energy metabolism (BEM). MCI occurs when there is a deficit in cognitive function and often has a high occurrence of progression toward Alzheimer's disease (AD). The goal of this study is to explore early biomarkers of neuronal function before AD diagnosis. Using P MRS techniques, cognitive performance of executive function in the parieto-occipital lobe indicated an inverse relationship between BEM indices and cognitive support. Individuals with higher BEM in the parieto-occipital lobes had lower cognitive performance. This suggests that there is potential for BEM utilization as a cognitive measure of MCI. 

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AUTHOR SPOTLIGHT

Jeffrey S. Spence, PhD

Director of Biostatistics

Audette Rackley, MS, CCC-SLP

Assistant Director, Strengths-Based Programs Research Clinician